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Triaminic Cough & Sore Throat (Acetaminophen Dextromethorphan HBr Pseudoephedrine HCl)

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Pharmacology
Acetaminophen produces analgesia and antipyresis by a mechanism similar to that of the salicylates.

Dextromethorphan is an antitussive. It is comparable to codeine in depressing the cough reflex. It has no expectorant action.

Pseudoephedrine is a nasal decongestant. It acts directly on the a-adrenergic receptors in the mucosa of the respiratory tract producing vasoconstriction. It shrinks swollen nasal mucous membranes, reduces tissue hyperemia, edema and nasal congestion, and increases nasal airway patency. Drainage of sinus secretions may be increased and obstructed eustachian ostia may be opened.

Indications
Acetaminophen Produces Analgesia And Antipyresis By A Mechanism Similar To That Of The Salicylates.

Dextromethorphan Is An Antitussive. It Is Comparable To Codeine In Depressing The Cough Reflex. It Has No Expectorant Action.

Pseudoephedrine Is A Nasal Decongestant. It Acts Directly On The A-adrenergic Receptors In The Mucosa Of The Respiratory Tract Producing Vasoconstriction. It Shrinks Swollen Nasal Mucous Membranes, Reduces Tissue Hyperemia, Edema And Nasal Congestion, And Increases Nasal Airway Patency. Drainage Of Sinus Secretions May Be Increased And Obstructed Eustachian Ostia May Be Opened.

Contraindications
 Hypersensitivity to any of the individual ingredients of the formulation, to the effect of other sympathomimetic amines and in patients with severe cardiovascular disorders.

This product should not be administered during or within 3 weeks following the administration of MAOIs (see Precautions, Drug Interactions ).

Safety Information / Warning
 This package contains enough drug to seriously harm a child. Keep out of reach of children.

Do not exceed recommended dose.

Do not take this product for persistent or chronic cough, or if you have chronic lung disease or shortness of breath, unless directed by a physician. A persistent cough may be a sign of a serious condition. Consult a physician if the underlying condition requires continued use for more than 5 days, tends to recur, or is accompanied by excessive secretions, high fever, rash or persistent headache.

This product contains sugar and is not recommended for diabetics.

Precautions
his product may cause drowsiness, excitability, nervousness, restlessness, sleeplessness and dizziness.

Individuals with high blood pressure, diabetes, glaucoma, heart, liver, thyroid or lung diseases, including asthma, difficulty in urination due to the enlargement of the prostate gland, the elderly, pregnant women and nursing mothers or persons on other medication, should take only as directed by a physician.

Children: Pseudoephedrine should only be used in infants on the advice of a physician, because of the higher than usual risk of side/adverse effects.

A physician or a pharmacist should be consulted prior to taking this medication in case of allergy to acetaminophen, chronic alcoholism, serious kidney or liver disease and/or intake of other medications containing acetaminophen and salicylates.

Significant Drug Interactions :  This product should not be administered during or within 3 weeks following the administration of MAOIs (see Contraindications).

Patients who are taking other medications containing acetaminophen or salicylates should consult a pharmacist or a physician before taking this product.

Avoid alcoholic beverages as well as other depressants, while taking this medicine.

Pregnancy  and Lactation:  Should not be used unless advised by the physician.

Side Effects / Adverse Effects
 Allergic reactions such as rash or itching, drowsiness, excitability, nervousness, restlessness, sleeplessness, dizziness.

Overdose
 Symptoms and Treatment:  In the case of accidental overdosage, contact a physician or Poison Control Centre immediately even if there are no symptoms.

Recommended Dosage
 Children 6 to 12 years: 10mL. Children 2 to 5 years: 5mL. Children under 2 years: Consult a physician.

Repeat every 6 hours. Do not exceed 4 doses in 24 hours.

Supplied / Packaging
Each 5mL of grape-flavored syrup contains: acetaminophen 160mg, dextromethorphan HBr 7.5mg and pseudoephedrine HCl 15mg. Nonmedicinal ingredients: benzoic acid, D&C Red No.33, disodium hydrogen phosphate, edetate disodium, FD&C Blue No.1, FD&C Red No.40, flavors, glycerin, polyethylene glycol, propylene glycol, sucrose, tartaric acid and water. Alcohol-free. Bottles of 100mL. Store at room temperature.

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