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Pharmacology
Methionine and cystine are amino-acids necessary for wound healing and forming of epithelial tissue.

Inositol acts as an essential growth factor and promotes epithelialization.

Urea aids in debridement, dissolves the coagulum and promotes epithelialization. Its solvent action on fibroblasts prevents the formation of excessive tissue, thus preventing stenosis when used as directed.

Sodium propionate is an antifungal agent.

Amino-Cerv is geared to the higher pH of the healthy cervix in contrast with pH4 vaginal preparations. With its pH factor of 5.5 it promotes faster healing of the cervix, yet will not adversely affect a healthy vagina.

Indications
Methionine And Cystine Are Amino-acids Necessary For Wound Healing And Forming Of Epithelial Tissue.

Inositol Acts As An Essential Growth Factor And Promotes Epithelialization.

Urea Aids In Debridement, Dissolves The Coagulum And Promotes Epithelialization. Its Solvent Action On Fibroblasts Prevents The Formation Of Excessive Tissue, Thus Preventing Stenosis When Used As Directed.

Sodium Propionate Is An Antifungal Agent.

Amino-Cerv Is Geared To The Higher PH Of The Healthy Cervix In Contrast With PH4 Vaginal Preparations. With Its PH Factor Of 5.5 It Promotes Faster Healing Of The Cervix, Yet Will Not Adversely Affect A Healthy Vagina.

Contraindications
Deleterious side effects have not been a problem at the doses recommended. The usual precautions against allergic reactions should be observed.

Safety Information / Warning
Information not available

Precautions
Information not available

Side Effects / Adverse Effects
Information not available

Overdose
Information not available

Recommended Dosage
When immediate postpartum bleeding has subsided (usually from 24to 48hours after delivery), 1Milex-Jector full of cream should be applied nightly for 4weeks. In mild cervicitis (not requiring cautery or cryosurgery), 1applicatorful of cream should be injected into the vagina nightly upon retiring for 2weeks. A small amount should be applied immediately following a surgical cervical procedure with the exception of a cold coning procedure. One applicatorful should be injected nightly upon retiring for 2to 4weeks (the duration of treatment depends on extent of the surgical procedure). In each of the post surgical visits, the physician should again apply a small amount of the cream with a probe or applicator. The canal is to be completely probed on the last visit.

After cold coning, 1applicatorful should be injected upon retiring about 24hours after surgery and nightly thereafter for 4weeks. During the 4weekly office visits following cold coning, a small amount of cream should be applied with a probe or applicator into the canal by the physician. The canal is to be completely probed on the last visit.

Reasons for Variation of Directions: After most surgical procedures, cauterization, cryosurgery and laser surgery, immediate use of Amino-Cerv is indicated to aid in dissolving dead or burned tissue.

After cold coning, there is no dead tissue to slough off. Therefore, a wait of 24hours or longer is desirable for normal healing to take place and for some fibroblasts to be laid down before applying the Amino-Cerv (which has a solvent action on both the fibroblasts and the absorbable sutures). When nonabsorbable  sutures are used, Amino-Cerv can be used immediately.

Supplied / Packaging
 Each g of cream contains: urea 8.34%, sodium propionate 0.5%, methionine 0.83%, cystine 0.35%, inositol 0.83% buffered to pH 5.5 in a water-miscible cream base. Tubes of 78g with or without Milex-Jector (2weeks' supply, 14applications). Store at room temperature.