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Triaminic Cold, Cough & Fever (Acetaminophen Chlorpheniramine Maleate Dextromethorphan HBr-Ps)
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Pharmacology
Acetaminophen produces analgesia and antipyresis by a mechanism similar to that of the salicylates.
Chlorpheniramine is an antihistamine (H-1 receptor antagonist) with less pronounced sedative effects. First generation antihistamines are considered effective in relieving rhinorrhea and sneezing associated with the common cold.
Dextromethorphan is an antitussive. It is comparable to codeine in depressing the cough reflex. It has no expectorant action.
Pseudoephedrine is a nasal decongestant. It acts directly on the a-adrenergic receptors in the mucosa of the respiratory tract producing vasoconstriction. It shrinks swollen nasal mucous membranes, reduces tissue hyperemia, edema and nasal congestion, and increases nasal airway patency. Drainage of sinus secretions may be increased and obstructed eustachian ostia may be opened.
Acetaminophen produces analgesia and antipyresis by a mechanism similar to that of the salicylates.
Chlorpheniramine is an antihistamine (H-1 receptor antagonist) with less pronounced sedative effects. First generation antihistamines are considered effective in relieving rhinorrhea and sneezing associated with the common cold.
Dextromethorphan is an antitussive. It is comparable to codeine in depressing the cough reflex. It has no expectorant action.
Pseudoephedrine is a nasal decongestant. It acts directly on the a-adrenergic receptors in the mucosa of the respiratory tract producing vasoconstriction. It shrinks swollen nasal mucous membranes, reduces tissue hyperemia, edema and nasal congestion, and increases nasal airway patency. Drainage of sinus secretions may be increased and obstructed eustachian ostia may be opened.
Indications
Acetaminophen Produces Analgesia And Antipyresis By A Mechanism Similar To That Of The Salicylates.
Chlorpheniramine Is An Antihistamine (H-1 Receptor Antagonist) With Less Pronounced Sedative Effects. First Generation Antihistamines Are Considered Effective In Relieving Rhinorrhea And Sneezing Associated With The Common Cold.
Dextromethorphan Is An Antitussive. It Is Comparable To Codeine In Depressing The Cough Reflex. It Has No Expectorant Action.
Pseudoephedrine Is A Nasal Decongestant. It Acts Directly On The A-adrenergic Receptors In The Mucosa Of The Respiratory Tract Producing Vasoconstriction. It Shrinks Swollen Nasal Mucous Membranes, Reduces Tissue Hyperemia, Edema And Nasal Congestion, And Increases Nasal Airway Patency. Drainage Of Sinus Secretions May Be Increased And Obstructed Eustachian Ostia May Be Opened.
Acetaminophen Produces Analgesia And Antipyresis By A Mechanism Similar To That Of The Salicylates.
Chlorpheniramine Is An Antihistamine (H-1 Receptor Antagonist) With Less Pronounced Sedative Effects. First Generation Antihistamines Are Considered Effective In Relieving Rhinorrhea And Sneezing Associated With The Common Cold.
Dextromethorphan Is An Antitussive. It Is Comparable To Codeine In Depressing The Cough Reflex. It Has No Expectorant Action.
Pseudoephedrine Is A Nasal Decongestant. It Acts Directly On The A-adrenergic Receptors In The Mucosa Of The Respiratory Tract Producing Vasoconstriction. It Shrinks Swollen Nasal Mucous Membranes, Reduces Tissue Hyperemia, Edema And Nasal Congestion, And Increases Nasal Airway Patency. Drainage Of Sinus Secretions May Be Increased And Obstructed Eustachian Ostia May Be Opened.
Contraindications
Hypersensitivity to any of the individual ingredients of the formulation, to the effect of other sympathomimetic amines and in patients with asthmatic attacks or severe cardiovascular disorders.
This product should not be administered during or within 3 weeks following the administration of MAOI's
Hypersensitivity to any of the individual ingredients of the formulation, to the effect of other sympathomimetic amines and in patients with asthmatic attacks or severe cardiovascular disorders.
This product should not be administered during or within 3 weeks following the administration of MAOI's
Safety Information / Warning
This package contains enough drug to seriously harm a child. Keep out of reach of children.
Do not exceed recommended dose.
Consult a physician if the underlying condition requires continued use for more than 5 days, tends to recur, or is accompanied by excessive secretions, high fever, rash or persistent headache.
Do not take this product for persistent or chronic cough, or if you have chronic lung disease or shortness of breath, unless directed by a physician. A persistent cough may be a sign of a serious condition.
Children: Antihistamines should not be given to children aged less than 1year because their sedative effect may be associated with episodes of sleep apnea.
This product contains sugar and is not recommended for diabetics.
This package contains enough drug to seriously harm a child. Keep out of reach of children.
Do not exceed recommended dose.
Consult a physician if the underlying condition requires continued use for more than 5 days, tends to recur, or is accompanied by excessive secretions, high fever, rash or persistent headache.
Do not take this product for persistent or chronic cough, or if you have chronic lung disease or shortness of breath, unless directed by a physician. A persistent cough may be a sign of a serious condition.
Children: Antihistamines should not be given to children aged less than 1year because their sedative effect may be associated with episodes of sleep apnea.
This product contains sugar and is not recommended for diabetics.
Precautions
This product may cause drowsiness, excitability, nervousness, restlessness, sleeplessness, dizziness and palpitations.
Individuals with epilepsy, high blood pressure, diabetes, glaucoma, heart, liver, thyroid or lung diseases, including asthma, bladder neck obstruction, stenosing peptic ulcer, pyloroduodenal obstruction, pregnant women and nursing mothers or persons on other medication, should take only as directed by a physician.
Children: Pseudoephedrine should only be used on the advice of a physician in infants, because of the higher than usual risk of side/adverse effects.
A physician or a pharmacist should be consulted prior to taking this medication in case of allergy to acetaminophen, chronic alcoholism, serious kidney or liver disease and/or intake of other medications containing acetaminophen and salicylates.
Significant Drug Interactions : This product should not be administered during or within 3 weeks following the administration of MAOI's (see Contraindications).
Patients who are taking other medications containing acetaminophen or salicylates should consult a pharmacist or a physician before taking this product.
Avoid alcoholic beverages as well as other depressants, while taking this medicine. Antihistamines should only be used under the direction of a physician in children receiving other CNS depressants (e.g. sedatives, tranquilizers).
Pregnancy and Lactation: Should not be used unless advised by the physician.
This product may cause drowsiness, excitability, nervousness, restlessness, sleeplessness, dizziness and palpitations.
Individuals with epilepsy, high blood pressure, diabetes, glaucoma, heart, liver, thyroid or lung diseases, including asthma, bladder neck obstruction, stenosing peptic ulcer, pyloroduodenal obstruction, pregnant women and nursing mothers or persons on other medication, should take only as directed by a physician.
Children: Pseudoephedrine should only be used on the advice of a physician in infants, because of the higher than usual risk of side/adverse effects.
A physician or a pharmacist should be consulted prior to taking this medication in case of allergy to acetaminophen, chronic alcoholism, serious kidney or liver disease and/or intake of other medications containing acetaminophen and salicylates.
Significant Drug Interactions : This product should not be administered during or within 3 weeks following the administration of MAOI's (see Contraindications).
Patients who are taking other medications containing acetaminophen or salicylates should consult a pharmacist or a physician before taking this product.
Avoid alcoholic beverages as well as other depressants, while taking this medicine. Antihistamines should only be used under the direction of a physician in children receiving other CNS depressants (e.g. sedatives, tranquilizers).
Pregnancy and Lactation: Should not be used unless advised by the physician.
Side Effects / Adverse Effects
Allergic reactions such as rash or itching, drowsiness, excitability, nervousness, restlessness, sleeplessness, dizziness and palpitations.
Allergic reactions such as rash or itching, drowsiness, excitability, nervousness, restlessness, sleeplessness, dizziness and palpitations.
Overdose
Symptoms and Treatment: In the case of accidental overdosage, contact a physician or Poison Control Centre immediately even if there are no symptoms.
Symptoms and Treatment: In the case of accidental overdosage, contact a physician or Poison Control Centre immediately even if there are no symptoms.
Recommended Dosage
Children 6to 12years: 10mL. Children 2to 5years: 5mL. Children under 2 years: Consult a physician.
May be repeated every 4 to 6 hours. Do not exceed 4doses in 24hours.
Children 6to 12years: 10mL. Children 2to 5years: 5mL. Children under 2 years: Consult a physician.
May be repeated every 4 to 6 hours. Do not exceed 4doses in 24hours.
Supplied / Packaging
Each 5mL of bubble gum flavored syrup contains: acetaminophen 160mg, dextromethorphan HBr 7.5mg, pseudoephedrine HCl 15mg and chlorpheniramine maleate 1mg. Nonmedicinal ingredients: acesulfame potassium, benzoic acid, citric acid, D&C Red No.33, edetate disodium, FD&C Red No. 40, flavors, glycerin, glycyrrhizic acid, polyethylene glycol, potassium chloride, potassium phosphate, propylene glycol, sucrose and water. Alcohol-free. Bottles of 100mL. Protect from light. Store at room temperature.
Each 5mL of bubble gum flavored syrup contains: acetaminophen 160mg, dextromethorphan HBr 7.5mg, pseudoephedrine HCl 15mg and chlorpheniramine maleate 1mg. Nonmedicinal ingredients: acesulfame potassium, benzoic acid, citric acid, D&C Red No.33, edetate disodium, FD&C Red No. 40, flavors, glycerin, glycyrrhizic acid, polyethylene glycol, potassium chloride, potassium phosphate, propylene glycol, sucrose and water. Alcohol-free. Bottles of 100mL. Protect from light. Store at room temperature.
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Brand Name
Triaminic Cold, Cough & Fever
Triaminic Cold, Cough & Fever
General Indications
Analgesic Antihistamine Antitussive Nasal Decongestant
Analgesic Antihistamine Antitussive Nasal Decongestant
